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目的:研究休克患者输血后出现的病情变化与再灌注综合征的关系。方法:回顾性总结分析1993年1月~1997年1月我院收治的18例非失血性休克患者输血前后临床表现比较。结果:18例患者均发生病情突然恶化,其中667%(12/18)发生在输血4~24h内,13例死亡,5例恢复正常。结论:休克患者输血后病情恶化可能与缺血再灌注损伤有关。提出对非失血性休克患者输血应持慎重态度,若必须输血,则应在休克早期进行,同时注意预防再灌注损伤。
Objective: To study the relationship between the changes of bloodstream and the reperfusion syndrome after blood transfusion in shock patients. Methods: The clinical manifestations of 18 patients with non-hemorrhagic shock treated in our hospital from January 1993 to January 1997 were retrospectively analyzed. Results: All of the 18 patients experienced sudden deterioration. Among them, 66.7% (12/18) occurred within 4 ~ 24h of blood transfusion, 13 died and 5 returned to normal. Conclusion: The worsening of blood transfusion in shock patients may be related to ischemia-reperfusion injury. Proposed non-hemorrhagic shock in patients with blood transfusion should hold a cautious attitude, if the need for blood transfusion, it should be carried out in the early shock, while paying attention to prevent reperfusion injury.