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目的:观察乳痛糖浆对小白鼠乳腺小叶增生病理组织学的抑制情况。方法:采用苯甲酸雌二醇小白鼠腹腔注射模,以不同剂量的乳痛糖浆及对照品乳癖消灌胃,然后进行病理组织学比较。结果:乳痛糖浆低、中、高剂量组与空白对照组比较,有非常显著性差异(P<0.01);乳痛糖浆高剂量组与乳癖消对照组比较,有显著性差异(P<0.05)。结论:提示采用高剂量乳痛糖浆治疗乳腺小叶增生可能产生更好的临床治疗效果。
Objective: To observe the inhibitory effect of Rutong syrup on the histopathology of lobular hyperplasia in mice. Methods: Estradiol benzoate mice were injected intraperitoneally with different doses of milk pain syrup and the control product Rupixiao. The histopathology was compared. RESULTS: There was a significant difference between the low-, medium-, and high-dose groups and the control group (P<0.01). There was a significant difference between the high-dose milk syrup group and the Ruqixiao group (P< 0.05). Conclusion: It is suggested that the use of high-dose milk pain syrup in the treatment of lobular hyperplasia of the breast may produce better clinical treatment.