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应用免疫组化ＳＰ法，观察了５７例鼻咽癌组织中的ＥＲ、ＰＲ表达情况。ＥＲ和ＰＲ的阳性率分别为４５．６１％（２６／５７）和４９．１２％（２８／５７）。临床分期及ＶｃＡ－ＩｇＡ滴度与ＥＲ、ＰＲ阳性率呈反相关性。结果亦表明：联合检测ＥＲ、ＰＲ及ＶｃＡ－ＩｇＡ滴度，可提高判断鼻咽癌预后的准确性，作者认为鼻咽癌应属于ＥＲ、ＰＲ高表达肿瘤，可考虑采用内分泌治疗。
Immunohistochemical SP method was used to observe the expression of ER and PR in 57 cases of nasopharyngeal carcinoma. The positive rates of ER and PR were 45.61% (26/57) and 49.12% (28/57) respectively. Clinical stage and VcA-IgA titers were inversely correlated with the positive rates of ER and PR. The results also show that: combined detection of ER, PR and VcA-IgA titers can improve the prognosis of NPC to determine the accuracy of the authors believe that nasopharyngeal carcinoma should belong to the ER, PR high expression of the tumor, consider the use of endocrine therapy.