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目的分析氨甲蝶呤与米非司酮配伍保守治疗异位妊娠的临床治疗效果。方法 80例异位妊娠患者,按照治疗方式分为研究组与对照组,每组40例。对照组患者采用单一的氨甲蝶呤进行治疗,研究组患者采用氨甲蝶呤与米非司酮配伍保守治疗,对两组患者的临床治疗效果展开观察与分析。结果治疗后,研究组患者黄体生成素、血孕酮素水平分别为(10.2±3.0)U/L、(2.2±0.2)nmol/L,显著优于对照组患者的(7.4±3.2)U/L、(7.0±2.1)nmol/L,差异有统计学意义(P<0.05)。两组雌二醇与卵泡刺激素水平比较,差异无统计学意义(P>0.05)。结论针对异位妊娠患者采用氨甲蝶呤与米非司酮进行配伍保守治疗能够有效减少患者临床不良反应症状,改善患者激素水平,临床治疗疗效显著。
Objective To analyze the clinical efficacy of methotrexate combined with mifepristone in the conservative treatment of ectopic pregnancy. Methods Eighty patients with ectopic pregnancy were divided into study group and control group according to the treatment mode, 40 cases in each group. Patients in the control group were treated with methotrexate alone. Patients in the study group were treated conservatively with methotrexate and mifepristone, and the clinical effects of the two groups were observed and analyzed. Results After treatment, the levels of luteinizing hormone and blood progesterone in the study group were (10.2 ± 3.0) U / L and (2.2 ± 0.2) nmol / L, respectively, which were significantly better than those in the control group (7.4 ± 3.2) U / L, (7.0 ± 2.1) nmol / L, the difference was statistically significant (P <0.05). The two groups of estradiol and follicle stimulating hormone levels, the difference was not statistically significant (P> 0.05). Conclusions The conservative treatment with methotrexate and mifepristone for patients with ectopic pregnancy can effectively reduce clinical symptoms and improve the hormone level in patients with clinical curative effect.