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目的:分析心房黏液瘤合并多发性颅内动脉瘤患者的临床及影像学资料,探讨其发病机制及其临床指导意义。方法:收集南方医科大学珠江医院神经内科自2005年1月至2010年6月收治10例心房黏液瘤合并多发性颅内动脉瘤患者的临床资料,进行为期3年的随访,分析其影像学特点和疗效。结果:8例患者的多发性颅内动脉瘤是在心房黏液瘤摘除术后半年或更长的时间发现;该类患者的主要临床表现为脑梗死或癫痫。CT平扫显示双侧大脑半球多发性结节样高密度灶,脑血管检查提示多发性颅内动脉瘤,前后循环均可受累。保守治疗病情平稳。结论:心房黏液瘤患者行黏液瘤摘除术后有出现迟发性多发性颅内动脉瘤的可能,术前及术后应定期行头颅影像学及脑血管检查。
Objective: To analyze the clinical and imaging data of patients with atrial myxoma complicated with intracranial aneurysm, and to explore its pathogenesis and clinical significance. Methods: The clinical data of 10 patients with atrial myxoma complicated with multiple intracranial aneurysms admitted to Department of Neurology, Zhujiang Hospital, Southern Medical University from January 2005 to June 2010 were collected and followed up for 3 years. The imaging features And efficacy. Results: The multiple intracranial aneurysms in 8 patients were found six months or more after atrial myxoma removal; the main clinical manifestations of these patients were cerebral infarction or epilepsy. CT scan showed multiple bilateral nodular hemispheric high-density lesions, cerebrovascular examination showed multiple intracranial aneurysms, before and after the cycle can be involved. Conservative treatment of a stable condition. Conclusions: Patients with atrial myxoma may have delayed multiple intracranial aneurysms after myxoma excision. Head and cranial imaging should be performed regularly before and after operation.