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目的对超过65岁社区获得性肺炎患者的临床特点、病因、预后进行分析,探索更加有效的治疗方法。方法选取2005年1月-2012年1月社区获得性肺炎老年患者84例,随机分为观察组和对照组各42例,分别给予莫西沙星、左氧氟沙星治疗。分析其指标菌组成及分析治疗效果。结果大多数患者有呼吸系统症状或体征;引起社区获得性肺炎的微生物以肺炎链球菌和嗜血杆菌的致病病原菌稍高;菌株清除率、总有效率观察组分别为95.2%、92.9%,对照组分别为85.7%、76.2%,两组比较差异均有统计学意义(均P<0.05)。结论虽然引起社区获得性肺炎的微生物区别不大,肺炎链球菌和嗜血杆菌的致病病原菌稍高,建议首先使用对链球菌和嗜血杆菌敏感的抗生素。
Objective To analyze the clinical features, causes and prognosis of patients with community-acquired pneumonia over 65 years old and to explore more effective treatment methods. Methods From January 2005 to January 2012, 84 elderly patients with community-acquired pneumonia were randomly divided into observation group (42 cases) and control group (42 cases), respectively. Moxifloxacin and levofloxacin were given respectively. Analysis of its indicator bacteria composition and analysis of treatment. Results Most of the patients had respiratory symptoms or signs. The pathogenic bacteria causing community-acquired pneumonia in S. pneumoniae and Haemophilus were slightly higher. The clearance rate and total effective rate in the observation group were 95.2%, 92.9% The control group were 85.7% and 76.2%, respectively, with significant difference between the two groups (all P <0.05). Conclusions Although there is not much difference between the microorganisms causing community-acquired pneumonia and the slightly higher pathogenic bacteria causing Streptococcus pneumoniae and Haemophilus, it is recommended to use antibiotics that are sensitive to Streptococcus and Haemophilus.