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目的了解广西宾阳县和上林县华支睾吸虫病的流行状况。方法采用随机抽样法选取调查对象,使用改良加藤法查华支睾吸虫虫卵;应用两级催化模型对人群华支睾吸虫感染情况进行分析。结果宾阳县和上林县人群华支睾吸虫感染率分别为82.90%(286/354)和40.06%(135/337),前者感染率明显高于后者,差异有统计学意义(χ2=1.203,P<0.005)。宾阳县和上林县人群华支睾吸虫感染率的两级催化模型曲线方程分别为y=1.05(e-0.006t-e-0.1225t)和y=1.83(e-0.0125t-e-0.0275t)。宾阳县a、b值分别为:a=0.122 5,b=0.006;上林县a、b值分别为:a=0.027 5,b=0.012 5。宾阳县各年龄组实际与理论感染率差异无统计学意义(P>0.05);上林县除10～19岁组外,各年龄组实际与理论感染率差异无统计学意义,两级催化曲线拟合良好。结论应用两级催化模型能很好地拟合宾阳和上林县人群华支睾吸虫病的流行状况,广西宾阳县和上林县均属重度流行区,宾阳县的传播速度大于上林县。
Objective To understand the prevalence of Clonorchis sinensis in Binyang County and Shanglin County of Guangxi. Methods The random sample method was used to select the subjects, and the improved method was used to detect Clonorchis sinensis eggs. The two-stage catalysis model was used to analyze the human clonorchis sinensis infection. Results The prevalences of Clonorchis sinensis in Binyang County and Shanglin County were 82.90% (286/354) and 40.06% (135/337), respectively. The former infection rate was significantly higher than the latter (χ2 = 1.203, P <0.005). The two-stage catalytic model curve equation of Clonorchis sinensis infection rate in Binyang County and Shanglin County was y = 1.05 (e-0.006t-e-0.1225t) and y = 1.83 (e-0.0125t-e-0.0275t), respectively. The values of a and b in Binyang County are a = 0.122 5 and b = 0.006, respectively. The values of a and b in Shanglin County are a = 0.027 5 and b = 0.012 5, respectively. There was no significant difference in actual and theoretical infection rates among all age groups in Binyang County (P> 0.05). There was no significant difference in actual and theoretical infection rates among all age groups in Shanglin County, Curve fit well. Conclusions The two-stage catalytic model can well fit the prevalence of Clonorchis sinensis in Binyang and Shanglin counties. Both Binyang and Shanglin counties in Guangxi are endemic and endemic to Binyang County, Lin County.