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目的对早产儿母乳喂养与新生儿坏死性小肠结肠炎的关系进行分析。方法收集中山市博爱医院胎龄≤36周、出生体重≤1800 g、符合入选条件的早产儿138例,根据喂养方式不同分为母乳喂养组63例,配方奶喂养组75例,对比分析两组患儿出现坏死性小肠结肠炎的发病情况,以及患儿的身高、体重发育情况。结果母乳喂养组坏死性小肠结肠炎发病率、感染性疾病发生率(1.37%、2.74%)与配方奶喂养组(20.00%、23.08%)相比明显较低,母乳喂养组患儿3个月、6个月胎龄时身高(59.88±8.69)cm、(67.65±6.84)cm与配方奶喂养组患儿身高(49.54±9.54)cm、(55.55±5.46)cm相比明显较高,母乳喂养组患儿3个月、6个月胎龄时体重(6.98±1.19)kg、(8.15±1.56)kg与配方奶喂养组患儿体重(5.12±0.78)kg、(6.97±1.38)kg相比明显较高,差异均有统计学意义(P<0.05)。结论早产儿母乳喂养可有效预防坏死性小肠结肠炎,并能促进新生儿生长发育,具有重要临床意义。
Objective To analyze the relationship between breast-feeding in premature infants and neonatal necrotizing enterocolitis. Methods Pok Oi Hospital of Zhongshan City, ≤ 36 weeks gestational age, birth weight ≤ 1800 g, meet the inclusion criteria 138 cases of premature children, divided into breastfeeding group according to different feeding 63 cases, formula feeding group 75 cases, comparative analysis of two groups Children with necrotizing enterocolitis incidence, as well as children’s height and weight development. Results The incidences of necrotizing enterocolitis and infectious diseases (1.37%, 2.74%) in breastfeeding group were significantly lower than those in formula feeding group (20.00%, 23.08%). The breastfeeding group had 3 months (59.88 ± 8.69) cm and (67.65 ± 6.84) cm at 6 months were significantly higher than that of the formula-fed group (49.54 ± 9.54 cm and 55.55 ± 5.46 cm, respectively. Breast-feeding The body weight (6.98 ± 1.19) kg and (8.15 ± 1.56) kg at 3 months and 6 months of gestation group were significantly higher than that of formula fed group (5.12 ± 0.78) kg and (6.97 ± 1.38) kg respectively Significantly higher, the difference was statistically significant (P <0.05). Conclusion Breastfeeding in preterm infants can effectively prevent necrotizing enterocolitis and promote neonatal growth and development, which has important clinical significance.