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巨形色痣是一种少见的上皮肿瘤,出生时即存在,甚大,占躯干及四肢大部分,有毛。痣细胞在真皮内,为神经外胚层的变异,能产生黑素。约30%恶性变。我院见到一例,现报告如下。谢××,男,6岁。1980年11月10日以右上肢及胸背部皮肤灰黑伴长毛为主诉就医。患儿系第二胎足月顺产,生后即见右上肢和胸背部皮肤灰黑,且有纤长的毳毛。随年龄长大,黑皮面积渐大,毛渐长粗而黑。各种感觉及排汗机能均正常。每年春季黑皮上发生一过性散在的灰黑色小丘疹,搔痒,溃疡后其基底部仍呈灰黑色。母乳喂养,9个月长牙,1岁说话,1.5岁走路,未出过麻疹,亦无其它传染病史。其母怀孕4个月时曾患过疟疾10余天,未治自愈,后未复发。无流感、风疹、过敏史及服药史。父母素健,非近亲婚配。第一胎女性,现年8岁,第三、四胎均女性,健在。查双亲四代26人均无类似情况及其它遗传病史。体检:体温37℃,脉搏90次/分,呼吸
Juvenile giant nevus is a rare epithelial tumor that exists at birth, very large, accounting for most of the trunk and limbs, hairy. Mole cells in the dermis, a variation of neuroectoderm, can produce melanin. About 30% of malignant changes. I saw a hospital, are as follows. Xie × ×, male, 6 years old. November 10, 1980 to the right upper extremity and chest and back skin gray chief with the chief complaint. Pediatric second-term fetus full-term follow-up, after birth, see the right upper extremity and chest and back skin gray, and slender beard hair. Grow with age, black skin area gradually enlarged, thick and thick fur. A variety of feeling and perspiration function are normal. Every spring on the black skin occurred in a scattered gray-black papules, itching, ulcers after the base is still gray-black. Breastfeeding, 9 months long teeth, 1 year old, 1.5 years old, no measles, nor any other infectious disease history. His mother had 4 months of pregnancy had malaria more than 10 days, did not cure self-healing, did not relapse. No flu, rubella, allergy history and medication history. Parents Su Jian, non-relatives of marriage. The first child of a woman, now 8 years old, third and fourth child are women, alive. Check the parents of four generations of 26 people without a similar situation and other genetic history. Physical examination: body temperature 37 ℃, pulse 90 beats / min, breathing