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用免疫细胞化学方法结合体视学分析，研究了Wistar大鼠的听源性惊厥易感大鼠（P77PMC）惊厥和点燃后海马结构内生长相关蛋白表达的差异、结果显示：（1）P77PMC大鼠一次惊厥后，海马结构内有广泛的生长相关蛋白免疫反应产物沉积，其分布呈板层样；（2）P77PMC大鼠点燃后，生长相关蛋白免疫反应产物的分布特征与一次惊厥后相比较，无明显变化，但是，海马CA3区苔藓纤维层生长相关蛋白免疫反应产物的光密度值显著增加（P＜0．01）。结果表明，听源性惊厥点燃能够诱导海马结构内生长相关蛋白表达增加。本文还对生长相关蛋白表达增加的生物学意义进行了讨论．
Immunocytochemistry combined with stereological analysis was used to investigate the differences in the expression of growth-related proteins in hippocampal formation between convulsions in auditory seizure-prone (P77PMC) and ignited livers of Wistar rats. The results showed that: (1) P77PMC After a seizure in rats, there was a wide range of growth-related protein immunoreactive products in the hippocampal formation, with a distribution of lamellar samples. (2) The distribution of growth-related protein immunoreactive products in P77 PMC rats was similar to that after a seizure , But no significant changes. However, the optical density of protein-related immune response products in the moss fiber layer of hippocampus CA3 increased significantly (P <0.01). The results show that auditory convulsion can increase the expression of growth related protein in hippocampal formation. This article also discusses the biological implications of the increased expression of growth-related proteins.