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本文报道了广东地区各类实验动物近年来的微生物和寄生虫感染情况及监控。大鼠和小鼠中从未发现LCM感染,小鼠也从未检到EHF感染。普通级大小鼠的体外寄生虫感染较普遍。1990年曾发生大鼠EHFV感染并致接触大鼠工作人员致病。近几年大鼠的EHF感染率明显下降,1990年为9.71%,1991年为0,1992年为0.89%,1993年为0.79%。小鼠Ect感染历年都有发生,感染率在1989年为0,1990年为1.4%,1991年为10.5%,1992年为2.8%。1993年为0.9%。曾发现临床症状和病理剖检诊断为Ect感染的BLAB/c和NIH小鼠群但血清末检出Ect抗体阳性。另外,SPF级裸鼠易发生金葡萄菌和绿脓杆菌感染。曾发现NC裸小鼠存在肝炎病毒感染,经追踪源于从外地引入时感染所致。在开放式饲养小鼠中,存在隐孢子虫和轮状病毒感染但无症状的感染个体。通过隔离和淘汰等措施,在Beagle犬群中排除了布氏菌感染,但用于教学的大多来于散养本地犬,体内外寄生虫感染较严重,包括人畜共患寄生虫。免的蚧螨和痒螨为常见体外寄生虫,历年累计感染率为10.6%,兔瘟偶有发生,兔波氏菌也时有感染。1992年和1993年,恒河猴和食蟹猴的结核杆菌,志贺氏菌的感染率为0,B病毒和沙门氏菌感染率在恒河猴为26.1%和1.18%,在食蟹猴为14.7%和1.8%。
In this paper, we report the status of microorganisms and parasites in various experimental animals in Guangdong and their surveillance. LCM infection was never found in rats and mice, and mice never detected EHF infection. Common-size rats in vitro parasites infections are more common. EHFV infection occurred in rats in 1990 and caused contact with rats in the rat pathogenic. In recent years, the incidence of EHF infection in rats decreased significantly, from 9.71% in 1990 to 0.91% in 1991, 0.89% in 1992 and 0.79% in 1993. Ect infection in mice over the years have occurred, the infection rate in 1989 was 0 in 1990 was 1.4% in 1991 was 10.5% in 1992 2.8%. 0.9% in 1993. Have found the clinical symptoms and pathological examination diagnosed as Ect infection in BLAB / c and NIH mice group but the end of the sera were detected positive Ect antibody. In addition, SPF nude mice prone to Staphylococcus aureus and Pseudomonas aeruginosa infection. It has been found that NC nude mice have hepatitis virus infection, which is traced by infection when introduced from abroad. In open-fledged mice, there are infected but non-symptomatic individuals infected with Cryptosporidium and rotavirus. By means of isolation and elimination, brucellosis was excluded from Beagle dogs. However, most of the dogs used for teaching were free-range native dogs, which had serious infections in vivo and in vitro, including zoonotic parasites. Mites and mites mites are free of common ectoparasites, the cumulative infection rate over the years was 10.6%, rabbit plague occasionally occur, Bunny bacteria are also sometimes infected. In 1992 and 1993, the infection rates of Mycobacterium tuberculosis and Shigella in rhesus macaques and cynomolgus monkeys were 0, the infection rates of B virus and Salmonella were 26.1% and 1.18% in rhesus monkeys, 14.7% and 1.8%.