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对于黄体期缺陷(LPD)的治疗是有争论的。本工作调查35例LPD患者的妊娠结果。LPD的诊断是在黄体期第12天时,两次子宫内膜活检异常的基础上建立的。患者无输卵管疾病,性交后试验无异常。 6例患者系高催乳素血症,用溴隐亭治疗后4例妊娠成功。余29例患者按照一有顺序的方案治疗,规定治疗6个月内未妊娠为治疗失败。治疗期间作子宫内膜活检,以明确LPD是否被纠正。首先经阴道给予孕酮25mg,一天两次。有2例患者不接受治疗;15例患者内膜活检显示LPD被纠正(56%),其中13人妊娠成功,1人连续两
The treatment of luteal phase defects (LPD) is controversial. The work of 35 cases of LPD pregnancy survey results. The diagnosis of LPD was established on the basis of two abnormal endometrial biopsies on day 12 of luteal phase. Patients without tubal disease, no abnormalities after the intercourse test. 6 patients were hyperprolactinemia, and 4 cases were successfully treated with bromocriptine. The remaining 29 patients were treated according to an ordered regimen, which provided for treatment failure within 6 months of non-pregnancy. Endometrial biopsies were taken during treatment to determine if LPD was corrected. First, vaginal administration of progesterone 25mg twice a day. Two patients did not receive treatment; 15 patients with endometrial biopsy showed that LPD was corrected (56%), of which 13 were successful in pregnancy, one for two consecutive