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目的:评估儿童变应性鼻炎(AR)患者的症状和生活质量,研究儿童AR患者症状的严重程度与生活质量的相关性,同时研究皮肤点刺试验结果与患儿症状、生活质量的相关性。方法:用症状视觉模拟评分量表(VAS)评价患儿症状的严重程度,用儿童鼻结膜炎相关生活质量问卷(RQLQ)评价患儿的生活质量,记录皮肤点刺试验结果,并进行相关的统计学分析。结果:①RQLQ量表5个方面间及23个项目间比较差异有统计学意义(F=32.03,P<0.01;F=7.35,P<0.01),鼻部症状方面是儿童患者生活质量最受影响的方面,其中鼻塞、喷嚏、鼻痒是评分最高的项目,三者间差异无统计学意义。②两量表有显著相关,其中难以入睡、因症状而觉得尴尬评分与鼻涕在VAS评分呈正相关(r=0.230,P<0.05;r=0.325,P<0.01),夜间醒来次数评分与鼻痒、喷嚏的VAS评分呈正相关(r=0.385,P<0.01;r=0.231,P<0.05),注意力难以集中评分与难以入睡、夜间醒来次数评分呈正相关(r=0.316,P<0.01;r=0.525,P<0.01),易怒评分与难以入睡评分呈正相关(r=0.243,P<0.05)。③皮肤点刺试验结果与两量表的各方面及总分均无显著相关。结论:AR患儿鼻部症状的严重程度与其生活质量显著相关,鼻涕、鼻痒、喷嚏可能是影响睡眠质量的主要原因,而睡眠质量可能影响非鼻眼部症状和情感反应,鼻涕可能是导致患儿因症状而觉得尴尬的主要原因;变应原级别与症状的严重程度及生活质量无显著相关。
OBJECTIVE: To assess the symptoms and quality of life in children with allergic rhinitis (AR) and to study the correlation between the severity of symptoms and quality of life in children with AR. To study the correlation between the results of skin prick test and children’s symptoms and quality of life . Methods: The severity of symptoms in children was evaluated by visual analog scale (VAS). The quality of life of children was evaluated by questionnaire of children’s rhinoconjunctivitis quality of life (RQLQ). Results of skin prick tests were recorded and correlated Statistical analysis. Results: ①RQQ was significantly different in 5 aspects and 23 items (F = 32.03, P <0.01; F = 7.35, P <0.01), and nasal symptoms were the most affected Among them, stuffy nose, sneeze, nasal itching are the items with the highest score, the difference between the three is not statistically significant. (2) There was a significant correlation between the two scales, in which it was difficult to fall asleep, and embarrassment scores due to symptoms were positively correlated with nasal discharge in VAS score (r = 0.230, P <0.05; r = 0.325, P <0.01) (R = 0.385, P <0.01; r = 0.231, P <0.05). There was a positive correlation between scores of attention difficulty difficulty falling asleep and nocturnal awakenings (r = 0.316, P <0.01) ; r = 0.525, P <0.01). There was a positive correlation between irritability score and difficulty falling asleep score (r = 0.243, P <0.05). ③ skin prick test results with the two scales in all aspects and the total score was no significant correlation. CONCLUSIONS: The severity of nasal symptoms in children with AR was significantly associated with their quality of life. Nasal discharge, nasal itching, and sneezing may be the main causes of sleep quality, while sleep quality may affect non-nasal ocular symptoms and emotional responses, and nasal discharge may be the cause The main cause of embarrassment in children with symptoms; the level of allergens did not correlate with the severity of symptoms and quality of life.