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目的 :探讨肾移植受者术后CsA血药浓度与RBC数及HGB含量的相关性。方法 :应用FPIA法测定 40例肾移植受者术后CsA血药浓度 ,分析术后不同时间RBC数及HGB含量对CsA血药浓度的影响。结果 :在术后早期CsA用量基本不变的情况下 ,CsA血药浓度与RBC数及HGB含量有显著正相关。结论 :术后早期RBC和HGB可能是影响CsA血药浓度的因素之一
Objective: To investigate the correlation between CsA serum concentration and RBC count and HGB content in renal transplant recipients. Methods: The plasma concentrations of CsA in 40 renal transplant recipients were measured by FPIA method. The effects of RBC count and HGB content on the plasma concentration of CsA were analyzed. Results: There was a significant positive correlation between CsA concentration and the number of RBCs and HGB in the early postoperative CsA dose was basically unchanged. Conclusions: Early postoperative RBC and HGB may be one of the factors affecting the serum concentration of CsA