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为了防止心肌梗塞的范围扩大,在发病早期使用血栓溶解药的治疗方法,已应用很久。但此种全身性的使用方法,到达血栓部位的药物,其量甚微,是否有效,短时间内能否溶解血栓均属不明。 通过动物实验证实:在梗塞早期应用导管将溶栓药尿激酶注入冠状动脉后,可在10～20分内溶栓,并且证实全身用药在短时间内不能起溶栓作用。本文作者从1980年夏开始应用于临床证明:局部纤溶疗法(用尿激酶)亦可在10～20分内使血栓溶解。一个月后再次造影证
In order to prevent the expansion of the scope of myocardial infarction, the treatment of thrombolytic drugs in the early stages of the disease has been used for a long time. However, this systemic use of drugs to reach the site of thrombosis, the amount is very small, effective, short-term dissolution of thrombosis are unknown. Animal experiments confirmed that: the early application of catheter infusion of thrombolytic drug urokinase into the coronary artery, can be thrombolytic within 10 to 20 minutes, and confirmed that systemic medication in a short time can not act as a thrombolytic effect. The authors applied clinical evidence from the summer of 1980: local fibrinolytic therapy (with urokinase) can also thrombolytic in 10 to 20 minutes. A month after making contrast film