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目的通过对江西省首例人感染H5N6禽流感病例的调查分析,探讨人感染H5N6禽流感感染因素。方法调查病例的发病就诊经过、可能的暴露来源,医学观察密切接触者,采集病例鼻咽拭子标本、暴露环境标本进行实验室检测,运用描述流行病学方法进行分析。结果江西省首例人感染H5N6禽流感患者,咽拭子标本检测为H5N6禽流感病毒核酸阳性,为外地感染,有活禽暴露史,医学观察密切接触者25人未发现异常;病例明确诊断较晚,有基础性疾病史,早期缺乏针对性治疗,导致病情加重,最后因呼吸衰竭死亡。结论江西省人感染H5N6禽流感病例可能与活禽暴露有关。
Objective To investigate the human infection of H5N6 bird flu in the first case of human infection of H5N6 in Jiangxi Province. Methods Investigate the pathogenesis of cases, probable sources of exposure, medical observation of close contacts, acquisition of nasopharyngeal swab specimens of patients, exposure of environmental specimens for laboratory testing, the use of descriptive epidemiological methods for analysis. Results The first case of H5N6 bird flu was detected in Jiangxi Province. The throat swab was positive for the H5N6 bird flu virus. It was a field infection and had live poultry exposure history. 25 cases of close contact with medical observation found no abnormality. Late, there is a history of basic diseases, early lack of targeted treatment, leading to aggravating conditions, and finally died of respiratory failure. Conclusion The cases of H5N6 bird flu in Jiangxi Province may be related to the live poultry exposure.