论文部分内容阅读
慢性肝病,尤其是肝硬化、肝癌时机体的防御能力降低,易引起肠内细菌丛的变化和内毒素血症。而且患者白细胞趋化作用减弱,并胃粘膜幽门螺杆菌(Hp)的感染率增高,一方面可致高氨血症,诱发肝性脑病发生;另一方面对胃粘膜的损伤作用,可导致慢性胃炎、消化性溃疡等疾病发生。因此,多数人主张对慢性肝病患者应作常规胃镜检查,判定有无Hp感染,如为阳性,则应及时用抗Hp药物治疗,这对于肝病本身或减少慢性胃病的发生均有重要的临床意义。
Chronic liver disease, especially cirrhosis and liver cancer, reduces the body’s defenses and easily causes changes in intestinal flora and endotoxemia. And patients with weakened leukocyte chemotaxis, and gastric mucosal Helicobacter pylori (Hp) infection rate increased, on the one hand can cause hyperammonemia, induced hepatic encephalopathy; the other hand, the role of gastric mucosal injury can lead to chronic Gastritis, peptic ulcer and other diseases. Therefore, most people advocate that patients with chronic liver disease should be routine gastroscopy to determine whether there is Hp infection, if positive, should be promptly treated with anti-Hp drugs, which for liver disease itself or reduce the incidence of chronic gastritis have important clinical significance .