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目的 探讨消化道平滑肌肉瘤的临床病理学特征 ,以提高其诊断及治疗水平。方法 回顾分析本院 1975～ 1996年间收治的消化道平滑肌肉瘤 86例。结果 本病缺乏特异临床症状 ,诊断比较困难 ,主要依靠病理检查中的核分裂相 ;以局限性生长者多见 ,手术切除率为 86% ;术后局部复发者较多 ,占 2 2 5 % ;生存率较低 ,胃、小肠及大肠平滑肌肉瘤的 5年生存率分别为 3 0 %、4 6 1%及 4 1 7%。结论 本病虽多能切除 ,但其复发率高 ,生存率低 ,欲提高其疗效 ,有赖于早期诊断 ,在肿瘤较小时得到根治及无瘤技术的应用
Objective To investigate the clinicopathological features of gastrointestinal leiomyosarcoma in order to improve its diagnosis and treatment. Methods Retrospective analysis of 86 cases of gastrointestinal leiomyosarcoma admitted to our hospital from 1975 to 1996. The results of the lack of specific clinical symptoms of this disease, the diagnosis is more difficult, mainly depends on the pathological examination of the mitotic phase; to more common growth limitations, surgical resection rate was 86%; postoperative local recurrence were more (225%); The 5-year survival rates of gastric, small intestine and large intestine leiomyosarcoma were 30%, 41% and 41.7%, respectively. Conclusion Although the disease can be resected more, but its high recurrence rate, low survival rate, to improve its efficacy, depends on the early diagnosis, when the tumor is small, radical and tumor-free technique