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七氟醚无明显刺激味,在血和组织中溶解度低,药物排除快;而异丙酚则具有诱导迅速平稳,苏醒快而完全及术后并发症少的优点。故二者均适用于非住院小儿外科手术。但最近有报道七氟醚麻醉后激动和不安的发生率比氟烷高。作者为比较异丙酚与七氟醚麻醉后小儿的苏醒质量(quality of recovery),选择50名ASAⅠ～Ⅱ级择期做扁桃体摘除术儿童(3～10岁),随机接受异丙酚麻醉(P组,n=25,静注异丙酚3mg·kg~(-1)诱导,100～250μg·kg~(-1)·min~(-1)维持);七氟醚麻醉(S组,n=25,吸7vol％七氟醚-N_2O-O_2诱导和(2～3)vol％七氟醚-N_2O-O_2维持)。两组均在静注阿芬太尼20μg·kg~(-1)和阿曲库铵0.5mg·kg~(-1)后气管插管,控制呼吸维持
Sevoflurane no obvious stimulus, low solubility in blood and tissues, drug exclusion; and propofol has the advantages of rapid and stable induction, rapid and complete recovery and less postoperative complications. So both are suitable for non-hospital pediatric surgery. However, it has recently been reported that the incidence of irritation and anxiety after sevoflurane anesthesia is higher than that of halothane. To compare the quality of recovery of children after anesthesia with propofol and sevoflurane, 50 children with ASA grade Ⅰ ~ Ⅱ elective tonsillectomy (3-10 years) were enrolled and were randomly assigned to receive propofol anesthesia (P (N = 25, intravenous propofol 3mg · kg -1, 100 ~ 250μg · kg -1 · min -1), sevoflurane anesthesia (group S, n = 25, induced by 7 vol% sevoflurane-N 2 O 2 and maintained at (2 ~ 3) vol% sevoflurane-N 2 O 2. Both groups were given tracheal intubation after intravenous injection of 20 μg · kg -1 of alfentanil and 0.5 mg · kg -1 of atracurium so as to control the respiration