Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-si RN

• 作 者: YunShi Si-YeWang MinYao Wen-Li
• 机 构: ResearchCenterofClinicalMedicineAffiliatedHospitalofNantongUniversity,DepartmentofImmunologyMedicalS
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2015年45期
• 关键词: HEPATOCELLULAR carcinoma NUCLEAR factorκB Multidru Hepatocellular carcinomaNucle
• 基金项目: Supported by Grants from the Jiangsu Provincial Special Programs of Medical Science； BL2012053； HK201102； the Nantong Undertaking and Technological Innovation； HS2013007； BK2013048 and HS2014078； the

AIM: To investigate small interfering RNA(si RNA)-mediated inhibition of nuclear factor-kappa B(NF-κB) activation and multidrug-resistant(MDR) phenotype formation in human Hep G2 cells. METHODS: Total RNA was extracted from human Hep G2 or LO2 cells. NF-κ