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目的了解寿光市农村居民乙肝病毒感染情况,为下一步乙型肝炎防治提供科学依据。方法 2010~2012年对寿光市所有农村居民进行一次HBsAg检测,阳性者进行ALT检测。结果检测357 082人,HBsAg阳性9 730例,阳性率为2.72%,其中ALT异常466例,异常率为4.79%。HBsAg阳性率,男性为3.26%,女性为2.24%(P<0.01);最高的镇为圣城街道,最低的镇为稻田镇;30~39岁组最高,为3.69%,<10岁组最低,为0.37%。HBsAg阳性者中ALT异常率,男性为5.61%,女性为3.71%(P<0.05);最高的镇为台头镇,最低的镇为圣城街道;各年龄组最高为40~49岁的6.24%,最低为<10岁组的2.78%。不同镇(街道)、不同年龄居民HBsAg阳性率和阳性者ALT异常率之间差异均有统计学意义(P<0.05)。结论寿光市乙肝病毒慢性感染者以青壮年较多,男性多于女性,工业发达流动人口较多的镇(街道)高于以务农为主的镇(街道)。
Objective To understand the status of hepatitis B virus infection among rural residents in Shouguang City and provide a scientific basis for the prevention and treatment of hepatitis B in the next step. Methods From 2010 to 2012, all rural residents in Shouguang City were tested for HBsAg, and those who were positive were tested for ALT. Results A total of 357 082 persons were tested, and 9 730 HBsAg positive were detected. The positive rate was 2.72%. There were 466 cases with abnormal ALT, the abnormal rate was 4.79%. The positive rate of HBsAg was 3.26% in males and 2.24% in females (P <0.01). The highest town was Sacred Street and the lowest was Paddy. The highest was 3.69% in 30-39 years old and lowest in <10 years , 0.37%. The abnormal rate of ALT in HBsAg positive patients was 5.61% for males and 3.71% for females (P <0.05). The highest town was Taitou town and the lowest town was the holy city street. The highest incidence of ALT in all age groups was 40-49 years %, A minimum of 2.78% of the <10-year-old group. In different towns (streets), the HBsAg positive rate of residents of different ages and positive ALT abnormalities were significantly different (P <0.05). Conclusion Chronic hepatitis B virus infection in Shouguang City is more frequent in young adults than in females. The town (street) with more industrialized floating population is higher than the town (street) dominated by farming.