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1981年瑞典的Hakanson提出的甘油注射疗法(GIJ)治疗三叉神经痛,现已成为最新的治疗手段。开始,Hakanson试验用放射线照射半月神经节获得去痛效果。这样就需用X线标记半月神经节的位置。半月神经节位于颅中窝后内侧的美克耳氏腔内的蛛网膜下腔(称为三叉神经沟),为此他用长针将稀有金属钽与甘油的混合物经皮通过卵圆孔注入三叉神经沟内。由于钽可能长时间停留在这一部位,故在X线上可随时定位。由于一个偶然机会,他向三叉神经沟只注入了甘油一种药物,结果发现三叉神经病症状竟然
Glycerol Injection Therapy (GIJ), proposed by Hakanson in Sweden in 1981, to treat trigeminal neuralgia has now become the latest treatment. Beginning, Hakanson test radiation to half the ganglion to obtain pain relief effect. This requires X-ray marking of the location of the semilunar ganglion. The semilunar ganglion is located in the subarachnoid space (called the trigeminal groove) in the medial Clarke’s intracranial fossa, and for this he uses a long needle to inject a mixture of rare metal tantalum and glycerol percutaneously through the foramen ovale Trigeminal nerve groove. As tantalum may stay in this area for a long time, so X-ray can be positioned at any time. Due to a chance, he only injected glycerol into the trigeminal groove drug, and found that symptoms of trigeminal nerve unexpectedly