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临床诊治妊娠期肝内胆汁瘀积症(ICP)58例,发生率为4.9%(58∶1182)。由于ICP围产儿死亡率高,死胎发生突然难以预料。本文采用放射免疫法测定血清甘胆酸(CG)浓度、超声多普勒检测脐动脉血流S/D值、胎心宫缩图、B超等多项产前监护法,检测58例ICP患者和50例正常晚孕妇女,并对两组的检测结果和妊娠结局进行分析。结果提示;此监护可以汇集各单项监护的不同优势,有利于早期发现ICP胎儿宫内缺氧,指导临床选择适当的时机和方式终妊娠,具有十分重要的临床意义
Clinical diagnosis and treatment of intrahepatic cholestasis in pregnancy 58 cases, the incidence was 4.9% (58:1182). Due to high perinatal ICP mortality, stillbirth suddenly unexpected unpredictable. In this paper, radioimmunoassay of serum levels of glycocholic acid (CG), ultrasonic Doppler detection of umbilical artery blood flow S / D value, fetal heart uterine fibula, B ultrasound and many other prenatal care, detection of 58 cases of ICP patients And 50 normal pregnant women, and the test results and pregnancy outcomes of the two groups were analyzed. The results suggest that this monitoring can bring together the different advantages of each single custody, is conducive to early detection of fetal intrauterine fetal hypoxia, clinical guidance to choose the appropriate timing and manner of final pregnancy, has a very important clinical significance