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目的 :探讨左旋精氨酸在食管癌治疗中的作用。方法 :86例患者随机分为两组 ,实验组术前 15天静脉输注左旋精氨酸 0 .5g/kg·天 ,然后手术。标本行细胞凋亡检查 ,与对照组对比。结果 :实验组肿瘤细胞凋亡阳性率明显高于对照组。结论 :左旋精氨酸可引起食管癌细胞的凋亡 ,在食管癌治疗中有一定作用
Objective: To investigate the role of L-arginine in the treatment of esophageal cancer. Methods: Eighty-six patients were randomly divided into two groups. The experimental group received intravenous infusion of L-arginine 0.5 g / kg · day 15 days prior to surgery. Specimens were examined for apoptosis, compared with the control group. Results: The positive rate of apoptosis in experimental group was significantly higher than that in control group. Conclusion: L-arginine can induce the apoptosis of esophageal cancer cells and play a role in the treatment of esophageal cancer