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目的了解新疆某三甲医院维吾尔族、汉族患者人腺病毒36(HAd V-36)感染与肥胖、低密度脂蛋白胆固醇(LDL-C)的关系。方法对2013年6月至2014年10月新疆医科大学第一附属医院内科132例维吾尔族、汉族入院检查的患者进行调查,并测定HAd V-36感染率,按体重指数(BMI)、LDL-C水平分组分析。结果BMI<25(正常组)、25≤BMI<28(超重组)、BMI≥28(肥胖组)HAd V-36病毒抗体阳性检出率分别为6.88%、21.87%、36.59%(P<0.05);其中维吾尔族BMI<25、25≤BMI<28、BMI≥28 HAd V-36病毒抗体阳性检出率分别为4.76%、27.78%、36.60%(P<0.05);汉族BMI<25、25≤BMI<28、BMI≥28 HAd V-36病毒抗体阳性检出率分别为7.89%、14.29%、37.50%(P<0.05),但不同的BMI组维族及汉族比较病毒检出率差异无统计学意义(P>0.05)。LDLC<3.37mmol/L、LDL-C≥3.37 mmol/L组HAd V-36病毒抗体阳性检出率分别为12.20%,32%(P<0.05);其中维吾尔族LDL-C<3.37 mmol/L、LDL-C≥3.37 mmol/LHAd V-36病毒抗体阳性检出率分别为15%、37.50%(P<0.05);汉族LDL-C<3.37 mmol/L、LDL-C≥3.37 mmol/LHAd V-36病毒抗体阳性检出率分别为9.52%、26.93%(P<0.05)。但不同的LDL组维族及汉族病毒检出率比较差异无统计学意义(P>0.05)。结论 HAd V-36病毒感染与新疆维吾尔族及汉族肥胖、LDL密切相关,随着BMI指数的增加,HAd V-36病毒检出率越高;且LDL-C水平越高,HAd V-36病毒检出率越高。
Objective To investigate the relationship between HAd V-36 infection and obesity and low density lipoprotein cholesterol (LDL-C) in Uygur and Han nationality patients in a third-class hospital in Xinjiang. Methods A total of 132 Uighur and Han nationality admitted patients admitted to the First Affiliated Hospital of Xinjiang Medical University from June 2013 to October 2014 were investigated. The prevalence of HAd V-36 infection was measured. The body mass index (BMI), LDL- C level grouping analysis. Results The positive rates of HAd V-36 virus in BMI <25 (normal group), 25≤BMI <28 (overweight group), BMI≥28 (obesity group) were 6.88%, 21.87%, 36.59% ). The prevalence of HAd V-36 antibody was 4.76%, 27.78% and 36.60%, respectively (P <0.05), while the BMI was lower than 25.25 ≤BMI <28, BMI≥28 The positive detection rate of HAd V-36 virus antibody was 7.89%, 14.29% and 37.50%, respectively (P <0.05), but there was no statistical difference in the prevalence of virus among Uygur and Han nationalities in different BMI groups Significance (P> 0.05). The positive rates of HAd V-36 virus in LDLC <3.37mmol / L and LDL-C≥3.37mmol / L were 12.20% and 32%, respectively (P <0.05) , And the positive rates of LDL-C≥3.37 mmol / LHAd V-36 were respectively 15% and 37.50% (P <0.05); LDL-C was 3.37 mmol / L and LDL-C≥3.37 mmol / LHAd V -36 virus antibody positive rates were 9.52%, 26.93% (P <0.05). However, there was no significant difference in the detection rates of Uygur and Han among different LDL groups (P> 0.05). Conclusions HAd V-36 virus infection is closely related to obesity and LDL in Xinjiang Uygur and Han people. With the increase of BMI index, the detection rate of HAd V-36 virus is higher. The higher the LDL-C level, the higher the HAd V-36 virus The higher the detection rate.