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目的:探讨妈富隆与米非司酮治疗围绝经期功血的方法及疗效对比。方法:将2007年2月~2012年3月我科收入的128例患者随机均分为妈富隆组与米非司酮组,分别给予妈富隆、米非司酮治疗,记录并作回顾性分析。结果:妈富隆组总有效率大于米非司酮组且差异具有统计学意义(P<0.05);2组患者组间子宫内膜厚度差异无统计学意义(P>0.05)而组内治疗后小于治疗前且差异具有统计学意义(P<0.05)。结论:妈富隆治疗围绝经期功血的临床疗效优于米非司酮,而子宫内膜厚度改变及不良反应等方面基本相当。
Objective: To investigate the methods and efficacy of Marvelon and mifepristone in the treatment of peri-menopausal dysfunctional uterine bleeding. Methods: From February 2007 to March 2012, 128 patients in our department were randomly divided into Marvelon group and mifepristone group, treated with Marvelon and Mifepristone respectively. The data were recorded and retrospectively analyzed . Results: The total effective rate of Marvelon group was higher than that of mifepristone group (P <0.05). There was no significant difference between the two groups in the endometrial thickness (P> 0.05) Less than before treatment and the difference was statistically significant (P <0.05). Conclusion: Marvelon treatment of climacteric dysfunctional uterine bleeding in the clinical efficacy is better than mifepristone, while the endometrial thickness changes and adverse reactions are basically the same.