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目的探讨2型糖尿病患者血清脂蛋白水平及其与颈动脉粥样斑块的关系。方法选择我院2008年2月～2011年8月收治的2型糖尿病患者100例作为观察组,其中2型糖尿病患者无颈动脉粥样斑块者49例,2型糖尿病患者伴颈动脉粥样斑块者51例;同时选择50例健康体检者作为对照组;检测比较两组的血脂指标。结果对照组和2型糖尿病无颈动脉粥样斑块患者的血脂结果分析表明,TG指标有显著性差异(P<0.05)。2型糖尿病患者无颈动脉粥样斑块与2型糖尿病患者伴颈动脉粥样斑块的血脂结果分析表明,TC,HDL-C,TG指标有显著性差异,比较差异具有统计学意义(P<0.05)。结论在2型糖尿病的诊疗过程中,对血脂各项指标注意观察,及时采取相应的预防措施纠正血糖及降脂,排除和减少引发心血管疾病的致病因素。
Objective To investigate the relationship between serum lipoprotein level and carotid artery plaque in type 2 diabetic patients. Methods 100 cases of type 2 diabetic patients treated in our hospital from February 2008 to August 2011 were selected as the observation group. Among them, 49 cases were type 2 diabetic without carotid atherosclerotic plaque and 2 cases were type 2 diabetic with carotid atherosclerosis 51 cases of plaque; also selected 50 cases of healthy subjects as a control group; test compared the two groups of blood lipid markers. Results The results of lipids in control group and type 2 diabetic patients without carotid atherosclerotic plaque showed that there was a significant difference in TG (P <0.05). The results of lipid profile of patients with type 2 diabetes without carotid atherosclerosis and type 2 diabetes with carotid atherosclerotic plaque showed that TC, HDL-C and TG were significantly different (P <0.05). Conclusion During the diagnosis and treatment of type 2 diabetes mellitus, various indicators of blood lipids were observed and timely taken appropriate preventive measures to correct blood sugar and lipid-lowering, to exclude and reduce the risk of causing cardiovascular disease risk factors.