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利用转基因小鼠能够同时从空间和时间角度观察目的基因的活动规律,这是现有其它任何实验体系所不及的。目前基因调控研究的许多进展都是通过这套系统而取得的。本文介绍了它在基因调控研究中的一些特点和近年研究的主要进展。
The use of transgenic mice to observe both the spatial and temporal aspects of the activity of the gene of interest, which is beyond the scope of any other existing experimental system. Many of the current advances in gene regulation research have been achieved through this system. This article describes some of its features in gene regulation research and major advances in recent years.