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为研究模拟失重、低氧、气功及其复合作用对人体脂质过氧化及循环内皮细胞含量(CEC)的影响,受试者为15名19~21岁男性健康青年,分为单纯卧床组(WC)、卧床+低氧组(WH)和卧床+气功组(WQ)进行了17d的头低位-6°卧床实验。结果显示:(1)WC组随卧床模拟失重时间延长,血超氧化物歧化酶(SOD)活性显著增加,尿丙二醛(MDA)含量显著降低,与WC组相比,WH组卧床17d的血SOD活性增加,WQ组卧床7d的血SOD活性降低,而WH和WQ组的MDA无显著变化。表明时失重机体抗氧化能力增强,脂质过氧化水平降低,低氧、气功在卧床时对机体的SOD的活性有一定的影响。(2)WC组在卧床7d时CEC含量显著下降,在17d时恢复正常,表明机体在卧床条件下血CEC含量有一定的变化。提示:低氧对卧床机体的血CEC含量无明显影响,而气功使卧床7d的血CEC含量显著增加
To study the effects of simulated weightlessness, hypoxia, qigong and their combined effects on lipid peroxidation and circulating endothelial cell content (CEC) in human subjects, 15 healthy young men aged 19-21 were divided into two groups: WC), bed + hypoxia group (WH) and bed rest + Qigong group (WQ) for 17 days. The results showed that: (1) Compared with WC group, WC group had a significantly lower serum SOD activity and a significantly lower urinary malondialdehyde (MDA) content as compared with WC group Blood SOD activity increased, WQ group bed 7d blood SOD activity decreased, while WH and WQ group MDA no significant change. The results showed that when the body weight loss was increased, the antioxidant capacity of the body was enhanced, the level of lipid peroxidation was reduced, and the hypoxia and Qigong had a certain effect on the activity of SOD in the bed. (2) The content of CEC in WC group decreased significantly on the 7th day and remained normal on the 17th day, which indicated that the level of CEC in the WC group was changed in the bed. Hint: Hypoxia has no significant effect on the blood CEC content of the bed body, while Qigong significantly increases the blood CEC content in the bed for 7 days