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目的了解2009年广州市2例输入性登革热病例的流行病学、病原学检查特点。方法对患者及密切接触者流行病学及临床资料进行回顾性分析,采用免疫层析法、ELISA法对患者血清样本进行登革热IgM、IgG抗体检测,并采用PCR对病毒进行分型。结果两名患者均来自登革热疫区,出现乏力、发热、头痛等症状。患者的DEV-IgM均呈阳性,DEV-IgG呈阴性,病毒型别均为登革Ⅰ型。结论两名患者为实验室确诊病例,由于发现及时,患者救治方案正确,各项防控措施落实到位,2例患者均痊愈出院,未发生二代病例,疫情得到有效控制。
Objective To understand the epidemiological and etiological characteristics of two imported dengue cases in Guangzhou in 2009. Methods The epidemiological and clinical data of patients and close contacts were retrospectively analyzed. Immunochromatography and ELISA were used to detect the IgM and IgG of the serum samples of patients, and the viruses were typed by PCR. Results Both patients were from dengue fever-infected area, with symptoms of fatigue, fever and headache. Patients with DEV-IgM were positive, DEV-IgG was negative, the virus type are dengue type Ⅰ. Conclusions Two patients were laboratory confirmed cases. Because of the prompt treatment, the correct treatment plan and the implementation of various prevention and control measures, two patients were cured and discharged without second-generation cases, and the outbreak was effectively controlled.