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目的:研究影响帕金森病(PD)患者生活质量的相关因素。方法:对92例门诊PD患者,采用PDQ-39、UPDRSⅠ～Ⅳ、H&Y、SE、MMSE、HAMD(17项)和HAMA(14项)分别进行评定,并进行统计学分析。结果:PDQ39(PDQ运动能力、PDQ日常生活、PDQ情绪健康、PDQ耻辱感及PDQ社会支持)、UPDRS(Ⅱ和Ⅲ)、医药费用支出、抑郁和焦虑情绪、认知水平以及左旋多巴每日剂量等均是影响生活质量的主要因素。同时女性比男性更易有耻辱感;<55岁和>65岁的患者的生活质量更差。结论:运用药物改善PD患者的运动障碍是提高生活质量的重要前提,但同时还要关注患者的情绪、社会功能等情况,尤其对女性、年龄>55岁和<65岁的患者。
Objective: To study the factors that influence the quality of life in patients with Parkinson’s disease (PD). Methods: Ninety-two outpatients with PD were evaluated with PDQ-39, UPDRS Ⅰ ~ Ⅳ, H & Y, SE, MMSE, HAMD (17 items) and HAMA (14 items) respectively. Results: PDQ39 (PDQ motor performance, PDQ daily life, PDQ emotional health, PDQ stigma and PDQ social support), UPDRS (II and III), medical expenses, depression and anxiety, cognitive level and daily levodopa daily Dose and so are the main factors affecting the quality of life. At the same time, women are more likely to have a sense of disgrace than men; patients 55 and 65 have worse quality of life. CONCLUSIONS: The use of drugs to improve dyskinesia in PD patients is an important prerequisite for improving the quality of life. At the same time, attention should be paid to the patients’ mood and social functions, especially for women, patients 55 years old and 65 years old.