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目的 探讨外周血细胞参数与肝硬化肝功能的关系。方法 用美国产雅培CD - 170 0型全自动血细胞分析仪对 32 1例肝硬化患者外周血进行检测分析。结果 肝硬化患者外周血细胞各项参数均显著异常 ,特别是红细胞参数血红蛋白 (Hb)、红细胞计数 (RBC)、红细胞压积 (HCT)、红细胞分布宽度 (RDW)改变与肝功能损害有很好的相关性。随着肝功能损害程度逐渐加重 ,Hb、RBC、HCT逐渐下降 ,RDW逐渐上升 (P <0 0 1)。结论 肝硬化患者外周血细胞参数变化与肝功能损害程度相关 ,其外周血细胞参数可间接反映肝硬化患者之肝功能损害的严重程度。
Objective To investigate the relationship between peripheral blood cell parameters and hepatic cirrhosis. Methods Peripheral blood samples from 32 patients with cirrhosis were detected by Abbott CD - 170 automatic hemocyte analyzer. Results The parameters of peripheral blood cells in patients with cirrhosis were significantly abnormal, especially the changes of erythrocyte hemoglobin (Hb), red blood cell count (RBC), hematocrit (HCT), width of erythrocytes distribution (RDW) and liver dysfunction Correlation. With the degree of liver damage gradually increased, Hb, RBC, HCT decreased gradually, RDW increased (P <0.01). Conclusion The changes of peripheral blood cells in patients with cirrhosis are related to the degree of liver damage. The parameters of peripheral blood cells can directly reflect the severity of liver dysfunction in cirrhotic patients.