论文部分内容阅读
目的分析耐药结核性脑膜炎(TBM)的疗效及预后。方法对2010年1月-2015年12月住院的32例成人耐药TBM患者病历资料进行回顾性分析并电话随访了解患者的预后情况,采用改良Rankin量表(m RS)对预后进行评分。结果 32例耐药TBM患者中好转31例(96.9%),治疗无效死亡1例(3.1%)。治疗后1例出现激素相关性青光眼及骨质疏松,1例出现药物性库欣综合征。27例(84.4%)患者m RS评分≤2分。结论耐药TBM早期诊断困难,经积极抗结核并辅助治疗,疗效满意。
Objective To analyze the efficacy and prognosis of drug-resistant tuberculous meningitis (TBM). Methods The clinical data of 32 adult patients with drug-resistant TBM admitted to our hospital from January 2010 to December 2015 were analyzed retrospectively. The prognosis of patients were analyzed by telephone follow-up. The prognosis was assessed by modified Rankin scale (m RS). Results Of the 32 patients with drug resistant TBM, 31 patients (96.9%) improved and 1 patient died (3.1%). One patient developed hormone-related glaucoma and osteoporosis after treatment, and one patient developed drug-induced Cushing’s syndrome. 27 patients (84.4%) m RS score ≤ 2 points. Conclusion The early diagnosis of drug resistant TBM is difficult, and the active anti-TB and adjuvant therapy are satisfactory.