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30例糖尿病患者的瞬目反射(BR)结果显示,糖尿病组左右两侧R1、R2、R2’各反应波潜伏期均值比较无显著差异(P>0.05),将两侧值平均后与正常人比较,各反应波潜伏期有不同程度的延长,以R2和R2’延长显著(P<0.01—0.001),且各波波幅均值低于正常人(P<0.001)。表明糖尿病性中枢神经系统损害可影响脑干,受损部位以桥脑为主。糖尿病病程与BR反应波的潜伏期异常率有一定关系,病程长的BR异常率高(P<0.05),而空腹血糖水平与BR反应波潜伏期异常率无一定关系(P>0.05)。BR对揭示临床症状不显的糖尿病性中枢神经系统损害可提供客观而灵敏的指标。
The blink reflex (BR) results of 30 diabetic patients showed that there was no significant difference (P> 0.05) between the mean values of R1, R2 and R2 ’latency in the left and right sides of the diabetes group, Compared with the control group, the latency of each response wave extended to different extents, with R2 and R2 ’prolonging significantly (P <0.01-0.001), and mean amplitude of each wave was lower than that of normal people (P <0.001). That diabetic central nervous system damage can affect the brain stem, damaged parts of the pontine-based. There was a relationship between the duration of diabetes and the abnormal rate of BR latency, and the longer duration of BR abnormality (P <0.05), while the fasting blood glucose level had no correlation with the abnormal latency of BR latency (P> 0.05) . BR provides objective and sensitive indicators of diabetic CNS damage that reveal no clinical signs.