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有效开展预防接种并对其效果作出评价,需要了解有关疾病各年龄抗体的存在情况。在采用麻疹、流行性腮腺炎和风疹疫苗之前,作者对这三种疾病病毒抗体各年龄的普遍情况进行了研究。1986～1987年,在英国不同地区的五个公共卫生实验室共收集血清标本8716份,人群的年龄范围在1≥65岁。结果在398份2岁以内儿童的血清标本中,60%(237份)无麻疹抗体。到3岁时降至30%。与之相比,在同龄儿童中,89%(354份)无流行性腮腺炎抗体,87%(347份)无风疹抗体,3～<5岁组对流行性腮腺炎的易感性急剧下降,对风疹的易感性下降则较晚。3～4岁组17%的儿童对麻疹易感,55%对流行性腮腺炎易感,73%对风疹易感。12岁以后,无麻疹
Effective vaccination and evaluation of its effectiveness requires knowledge of the presence of antibodies at all ages in the disease. Prior to the use of measles, mumps and rubella vaccines, the authors studied the prevalence of each age group of antibodies to these three diseases. From 1986 to 1987, a total of 8716 serum samples were collected from five public health laboratories in different parts of the UK. The age range of the population was 1≥65 years. Results Of the 398 serum samples of children under 2 years of age, 60% (237) had no measles antibody. By the age of 3 dropped to 30%. In contrast, 89% (354) of the children of the same age had no mumps antibodies and 87% (347) had no rubella antibodies and the susceptibility to mumps dropped sharply in the age group 3 to <5 years, Susceptibility to rubella decreased later. 17% of children in the age group 3 to 4 were susceptible to measles, 55% were susceptible to mumps, and 73% were susceptible to rubella. After 12 years of age, no measles