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目的探讨采用山莨菪碱全身和局部用药治疗Ⅱ级以上糖尿病足的治疗效果。方法设治疗组和对照组,两组在常规治疗的基础上,治疗组采用山莨菪碱全身静脉注射和局部滴注联合给药法,剂量分别为0.5～1.0mg/kg/d。结果实验组27例,显效23例;有效3例;无效1例,总有效率96.3%;对照组显效24例,有效11例,无效13例,总有效率45.8%;两组总有效率比较有非常显著性差异(P<0.01)。结论联合使用山莨菪碱全身及局部用药治疗糖尿病足明显优于常规治疗效果。
Objective To investigate the therapeutic effect of whole-body and topical application of anisodamine on diabetic patients with grade Ⅱ or higher. Methods The treatment group and the control group were established. On the basis of routine treatment, the two groups were treated with intravenous anisodamine intravenously and local drip infusion. The doses were 0.5-1.0 mg / kg / d. Results The experimental group of 27 cases, markedly effective in 23 cases; effective in 3 cases; ineffective in 1 case, the total effective rate was 96.3%; control group of 24 cases markedly effective in 11 cases, ineffective in 13 cases, the total effective rate was 45.8%; There is a very significant difference (P <0.01). Conclusion Combined use of Anisodamine whole body and topical treatment of diabetic foot was significantly better than the conventional treatment.