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目的:通过对比观察轻度贫血食管癌患者术中输血与否对围术期血流动力学及术后恢复状况的影响,以探讨病人术中不输血的安全性。方法:选择ASAI~Ⅱ级择期手术食管癌贫血病人80例,男性血红蛋白(Hb)范围在90g/L与120g/L之间,女性在90g/L与110g/L之间,随机分为输血组(T组)与非输血组(NT组)各40例,T组的Hb为(108.77.4)g/L,NT组的Hb为(109.36.4)g/L,全部采用气管插管静脉复合全麻。观察病人围术期血流动力学变化,随访术后切口愈合情况及并发症。结果:两组病人围术期血流动力学维持平稳,组间比较无明显差别(P>0.05);术后切口愈合良好(所有病例均为Ⅱ/甲愈合),T组有1例吻合口瘘和1例颈部切口感染,NT组无术后并发症发生。结论:术前轻度贫血食管瘤病人术中无特殊情况(如大出血)不输血是安全的。
Objective: To compare the effect of intraoperative blood transfusion on the hemodynamics and postoperative recovery in patients with mild anemia and esophageal cancer, in order to discuss the safety of transfusion without blood transfusion. METHODS: Eighty patients with anaesthesia for esophageal cancer undergoing elective ASA I-II surgery were selected. Male hemoglobin (Hb) ranged between 90 g/L and 120 g/L, and women were between 90 g/L and 110 g/L. They were randomly divided into blood transfusion groups. In the 40 cases (T group) and non-blood transfusion group (NT group), Hb of group T was (108.77.4) g/L, Hb of group NT was (109.36.4) g/L. Tracheal intubation and intravenous anesthesia. Perioperative hemodynamic changes were observed, and wound healing and complications were followed up. Results: Hemodynamics remained stable during the perioperative period in both groups. There was no significant difference between the two groups (P>0.05); postoperative incision healed well (all cases were II/A healing), and there was one case in group T. Anastomotic fistula and one case of neck incision infection, NT group no postoperative complications. Conclusion: It is safe for patients with preoperative mild anemia esophageal tumors to have no special conditions (such as major bleeding) without transfusion.