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目的探讨输卵管不通C形臂X光机引导下介入再通术后,经导管医用臭氧缓慢灌注输卵管,以降低再粘连,保持通畅性的可能性。方法 96例双侧输卵管性不孕患者,随机分成二组。观察组52例在介入治疗后向每侧开通后的输卵管注入医用臭氧10ml;对照组44例,介入治疗后向输卵管内注入0.9%氯化钠注射液20ml+地塞米松5mg+糜蛋白酶4 000U+庆大霉素8万U混合液。所有患者6、12个月后复查并对比二组的治疗有效率、妊娠率及再粘连率。结果观察组有效率86.34%,妊娠率47.61%,术后再粘连率14.89%;对照组有效率65.76%,妊娠率27.51%,术后再粘连率35.13%.观察组有效率及妊娠率高于对照组,术后再粘连率低于对照组,差异有统计学意义(P<0.05)。结论医用臭氧在输卵管不通介入治疗后可提高通畅率、妊娠率,并降低再粘连率。
Objective To investigate the possibility of tubal obstruction after fallopian tube C-arm X-ray machine interventional recanalization guided by catheter medical ozone slowly infusion tubal to reduce re-adhesion and maintain patency. Methods 96 cases of bilateral tubal infertility were randomly divided into two groups. In the observation group, 52 cases were injected with 10 ml of medical ozone into the fallopian tubes after the interventional treatment. In the control group, 44 cases were injected with 0.9% sodium chloride injection 20ml + dexamethasone 5mg + chymotrypsin 4000U + 80,000 U mixed solution of U. All patients were reviewed after 6 and 12 months and compared the two groups of treatment efficiency, pregnancy rate and re-adhesion rate. Results The observation group had an effective rate of 86.34%, a pregnancy rate of 47.61% and a re-adhesion rate of 14.89% in the control group, with an effective rate of 65.76%, a pregnancy rate of 27.51% and a re-adhesion rate of 35.13% In the control group, the rate of re-adhesion after operation was lower than that of the control group, with significant difference (P <0.05). Conclusion Medical ozone can improve patency, pregnancy rate and reduce the rate of re-adhesion after interventional treatment of fallopian tube.