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目的观察雌激素对绝经期妇女脑电图的影响。方法对６２名绝经期妇女前后二次进行脑电图监测。服药组中１３名绝经期＜５年，１７名绝经期＞５年，在一年中每隔１４天服维尼尔片一次，剂量分别为２ｍｇ／次和１ｍｇ／次。３２名未服药者为对照组。结果绝经期＜５年组服用雌激素后的脑电图异常率明显低于对照组（Ｐ＜００５），但绝经期＞５年者二组脑电图的异常率无显著差异性（Ｐ＞００５）。结论本文认为在绝经初期５年内给予补充雌激素口服能够改善脑电图的异常。
Objective To observe the effects of estrogen on the EEG of postmenopausal women. Methods Sixty-two menopausal women were monitored twice before and after EEG. Thirteen menopausal women <5 years and 17 menopausal women> 5 years in the medication group received vinorel tablets every other day for 14 days at doses of 2 mg and 1 mg respectively. 32 non-medication for the control group. Results The abnormal rate of EEG after taking estrogen in menopausal <5 years group was significantly lower than that in control group (P <005), but there was no significant difference in EEG abnormalities between the two groups when menopausal> 5 years P> 005). Conclusions This paper suggests that oral administration of estrogen orally during the first five years after menopause can improve EEG abnormalities.