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目的:探讨家庭医护信息化管理平台对结直肠癌化疗患者服药偏差、服药依从性及营养管理的影响。方法:采用便利抽样法，选择2018年3月—2019年6月在河南省人民医院接受化疗的64例结直肠癌患者为研究对象，根据随机数字表法分为对照组和观察组，每组各32例。对照组采用常规管理，观察组利用家庭医护信息化管理平台管理。于干预后采用服药偏差工具、中文版Morisky服药依从性量表比较两组患者的服药偏差发生率、服药依从性；采用BMI、血红蛋白、总蛋白、白蛋白及改良主观综合性营养评估（SGA）得分比较两组患者的营养情况。结果:干预后观察组服药偏差发生率为21.88%（7/32），低于对照组的62.50%（20/32），差异有统计学意义（χn 2=10.827，n P<0.01）。干预后两组患者服药依从性比较差异有统计学意义（n Z=2.207，n P<0.05）。干预后观察组患者BMI、血红蛋白、总蛋白及白蛋白高于对照组，改良SGA评分低于对照组，差异有统计学意义（n t值分别为-2.340、-3.007、-2.137、-3.334、3.107；n P<0.05）。干预后观察组患者营养正常例数多于对照组，重度营养不良例数少于对照组，差异有统计学意义（χn 2值分别为4.267、5.379；n P<0.05）。n 结论:家庭医护信息化管理平台的应用可以减少结直肠癌化疗患者服药偏差，提高患者服药依从性，减少营养不良状况的发生。“,”Objective:To explore effects of family medical information management platform on medication discrepancy, medication compliance and nutritional management of patients with colorectal cancer undergoing chemotherapy.Methods:Using the convenient sampling method, a total of 64 patients with colorectal cancer who received chemotherapy in Henan Provincial People's Hospital from March 2018 to June 2019 were selected as the research objects. According to the random number table method, they were divided into the control group and the observation group, with 32 cases in each group. The control group adopted conventional management, while the observation group adopted family medical information management platform. After intervention, Medication Discrepancy Tool (MDT) and the Chinese Version of Morisky Medication Compliance Scale were used to compare the incidence of medication discrepancy and medication compliance of patients of the two groups. The nutritional status of patients in the two groups was compared using BMI, hemoglobin, total protein, albumin and modified Subjective Global Assessment (SGA) scores.Results:After the intervention, the incidence of medication discrepancy in the observation group was 21.88% (7/32) , lower than 62.50% (20/32) in the control group, and the difference was statistically significant (χn 2=10.827, n P<0.01) . After the intervention, there was a statistically significant difference in medication compliance between the two groups (n Z=2.207, n P<0.05) . After intervention, BMI, hemoglobin, total protein and albumin of the observation group were higher than those of the control group, and the modified SGA score was lower than that of the control group, and the differences were statistically significant (n t=-2.340, -3.007, -2.137, -3.334, 3.107; n P<0.05) . After intervention, the number of normal nutritional cases in the observation group was higher than that in the control group, and the number of severe malnutrition cases was lower than that in the control group, and the differences were statistically significant (χn 2=4.267, 5.379; n P<0.05) .n Conclusions:The application of family medical information management platform can reduce medication discrepancy of patients with colorectal cancer undergoing chemotherapy, improve their medication compliance and reduce the occurrence of malnutrition.