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目的探讨银杏叶片对急性脑梗死患者血小板聚集率和阿司匹林抵抗的影响,并观察银杏叶片的临床疗效。方法选取在该院住院的急性脑梗死患者128例,随机均分为二组,对照组接受常规阿司匹林治疗,观察组在常规治疗的基础上加用银杏叶片治疗,分别于用药前和用药第十四天测定二组患者的血小板聚集率水平,并筛选阿司匹林抵抗患者,同时进行神经功能缺损评分。结果二组患者治疗后血小板聚集率较治疗前下降,且观察组较对照组明显降低;神经功能缺损显著改善,差异有统计学意义(P<0.05)。二组阿司匹林抵抗患者比较观察组少于对照组,差异有统计学意义(P<0.05)。结论银杏叶片可使急性脑梗死患者血小板聚集得到显著抑制,减少阿司匹林抵抗的发生,同时有助于改善患者的神经功能。
Objective To investigate the effect of Ginkgo biloba on platelet aggregation and aspirin resistance in patients with acute cerebral infarction and to observe the clinical efficacy of Ginkgo biloba leaf. Methods 128 patients with acute cerebral infarction hospitalized in the hospital were randomly divided into two groups. The control group received routine aspirin treatment. The observation group was treated with ginkgo leaf therapy on the basis of conventional treatment. Four days were measured in two groups of patients with platelet aggregation rate levels, and screening aspirin resistance in patients with neurological deficit score. Results The platelet aggregation rate of the two groups after treatment was lower than that before treatment, and the observation group was significantly lower than the control group. The neurological deficit was significantly improved (P <0.05). Two aspirin resistance patients in the observation group was less than the control group, the difference was statistically significant (P <0.05). Conclusion Ginkgo biloba leaves can significantly inhibit platelet aggregation in patients with acute cerebral infarction, reduce the occurrence of aspirin resistance, and help to improve the neurological function of patients.