IGF2 ApaI A/G Polymorphism Evaluated in ESRD Individuals as a Biomarker to Identify Patients with Ne

• 作 者: Kiran Kumar Vattam Imran Ali K
• 机 构: CenterofMedicalGenetics,DepartmentofBiochemistry,DepartmentofGeneticsandMolecularMedicine,Department
• 出 处: 肾脏病(英文)
• 发表日期: 2013年2期
• 关键词: PTDM IGF2 Gene POLYMORPHISM DIABETES MELLITUS ESRD New ONSET DIABETES MELLITUS P

Insulin like growth factors2 (IGF2) regulates pancreatic β-cell renewal and apoptosis, which in turn plays a role in altering insulin activity and glucose homeostasis. Polymorphisms in IGF2 gene have been associated with altered levels of IGF2. Hence, Apa