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T细胞抗原受体是由6个不同基因编码的至少含有7个跨膜肽单元组成的,虽经物种进化和遗传变异,T细胞受体的α链(TCRα)的跨膜肽序列在鼠、羊、牛及人各物种保持惊人的相似,提示它在介导T细胞功能上可能扮演重要角色。作者证明TCRα与CD3δ之间的固定反应集中于前者跨膜肽单元的8
T cell antigen receptor is encoded by six different genes containing at least seven transmembrane peptide units, although species evolution and genetic variation, T cell receptor α chain (TCRα) transmembrane peptide sequence in mice, Sheep, cow and human species keep a striking similarities, suggesting that it may play an important role in mediating T cell function. The authors demonstrate that the immobilization reaction between TCRα and CD3δ is focused on the 8