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在阴道内放置杀精剂进行避孕并不是什么新的避孕方法,这种方法存在着一定的缺点,但由于其副作用小,不影响全身的正常生理状态,而且使用也还算方便,因而仍为相当一部份的育龄夫妇所使用,成为当今常用的避孕措施之一。为了提高杀精剂的避孕效果、减小副作用,并使之应用时更为简便,近年来,各国科学家不仅合成了一些疗效更好的新药,而且在剂型和使用方法上也作了新的改进和探索。杀精的胶冻、片剂、栓剂、薄膜等相继问世,含杀精剂的阴道海绵块、缓慢释放的阴道环也开始投入临床使用。除此而外,在药物的临床试验前评价、临床试验程序、药物质量控制、安全性评价等方面也都进行了系统研究。1979年由Zatuchnl,G.L.,Sobrero,K.A.等编写、美国Harper & Row 出版社出版的《阴道避孕新发展》(Vaginal Contraception—New Develep-ments)一书,即为阴道避孕研究领域中少见的专著。它集中反映了当前国际上关于阴道避孕研究的最近进展,内容
It is not a new contraceptive method to place spermicide in the vagina for contraception. This method has certain disadvantages. However, due to its small side effects, it does not affect the normal physiological state of the whole body and is still convenient to use A considerable part of couples of childbearing age used to become one of the commonly used contraceptive measures today. In order to improve the contraceptive effect of spermicide, reduce the side effects and make it easier to use, in recent years, scientists from different countries have not only synthesized some new drugs with better curative effect, but also made new improvements in dosage forms and methods of use And explore. Spermicidal jelly, tablets, suppositories, films have come out in succession, with spermicidal vaginal sponge block, the slow release of the vaginal ring has also begun to put into clinical use. In addition, systematic studies have also been conducted on the evaluation of clinical trials of drugs, clinical trial procedures, quality control of drugs, and safety evaluation. The book Vaginal Contraception - New Develep-ments, written by Zatuchnl, G.L., Sobrero, K.A. et al. In 1979, is a rare monograph in the field of vaginal contraception. It focused on the current international research on vaginal contraception recent progress, content