论文部分内容阅读
目的:研究麦门冬汤联合EP方案治疗中晚期非小细胞肺癌的近期疗效及麦门冬汤对化疗的减毒增效的作用。方法:对19例中晚期非小细胞肺癌随机分为治疗组(中西医结合组)和对照组(西医组)。其中治疗组10例,对照组9例,两组均给予EP方案全身化疗,治疗组加服麦门冬汤并随症加减。连续观察3个化疗周期后比较两组治疗前后的不同。结果:治疗组客观有效率为70%,明显优于对照组的44.44%,有显著差异,P<0.05;治疗组的消化道毒性、血液学毒性分别为50%、50%,均明显低于对照组的77.77%、66.66%。结论:麦门冬汤联合EP方案治疗中晚期非小细胞肺癌,能够减轻化疗的不良反应,稳定肿瘤病灶,改善患者的生活质量,而且经济,比较适合年老体弱及经济落后地区非小细胞肺癌患者的姑息治疗,值得进一步深入研究。
OBJECTIVE: To study the short-term curative effect of combining MaiMenDong Decoction with EP regimen in the treatment of advanced non-small cell lung cancer (NSCLC) and the effect of MaiMenDong decoction on the attenuation and synergism of chemotherapy. Methods: Nineteen patients with advanced non-small cell lung cancer were randomly divided into treatment group (Integrative Medicine Group) and control group (Western medicine group). Among them, 10 cases in the treatment group and 9 cases in the control group were given systemic chemotherapy with EP. After 3 consecutive cycles of chemotherapy, the differences between before and after treatment were compared. Results: The objective effective rate in the treatment group was 70%, which was significantly better than that in the control group (44.44%, P <0.05). The gastrointestinal toxicity and hematological toxicity in the treatment group were 50% and 50% The control group 77.77%, 66.66%. Conclusions: Combination of MEomme soup and EP regimen in the treatment of advanced non-small cell lung cancer can reduce the adverse reactions of chemotherapy, stabilize the tumor lesions and improve the quality of life of patients, and it is more economical and suitable for the elderly and infirm non-small cell Palliative treatment of patients with lung cancer, it is worth further study.