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恶性网状细胞病是网状内皮系统肿瘤性疾病。最初被认为是不典型的何杰金氏病。1938年Scott及Robb-Smith根据淋巴结的标本材料,把它从何杰金氏病中分离出来,并提出用网状细胞增殖症(Reticulosis)这个名词来描述所有进行性网状内皮细胞增殖症的疾病。他们从组织学的观点出发,将网状细胞增殖症分为14型,其中一型组织细胞性髓性网织细胞增殖症(Histiocytic Medullary Reticulosis)即恶性网状细胞病。许多学者对网状内皮细胞系统疾病的定名、归类、临床病型及异型细胞的形
Malignant reticulosis is a neoplastic disease of the reticuloendothelial system. Hodgkin’s disease was originally considered atypical. In 1938, Scott and Robb-Smith isolated it from Hodgkin’s disease on the basis of lymph node specimens and proposed the use of the term Reticulosis to describe all of the progressive reticuloendothelial proliferative disease. From a histological point of view, they classify reticulocyte proliferative disorders into 14 types, one of which is Histiocytic Medullary Reticulosis, a malignant reticular cytopathy. Many scholars of the reticuloendothelial system diseases, naming, classification, clinical type and shaped cell shape