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采用具有不同间隔(0～32ms)的65dB nHL(正常听力水平)的成对短声刺激,记录20名正常人的单侧耳和两耳交替刺激的听觉脑干反应(ABR)。用计算机从成对短声反应中减去单一短声反应以提取衍生ABR。结果表明,单、双耳的衍生ABR V波振幅在成对短声间隔为0.2～1.5ms时,受到明显影响。单耳的减小54％～65％(P<0.01),两耳的减少46％～53％(P<0.01),但单、双耳的衍生ABR I波振幅未显示显著差异(P>0.05)。该结果说明,高位脑干通路在成对短声间隔为0.2～1.5ms时,不但对同侧耳的第2个短声反应能力降低,而且对来自对侧耳的第2个短声也如此。从而推断,在两耳交替刺激的耳间短声间隔小于2ms范围时,在下丘部位可能存在两耳交互作用。结果还提示,临床检查ABR时,采用的短声刺激间隔至少不应小于30ms。
The auditory brainstem response (ABR), alternating between unilateral ears and both ears of 20 normal subjects, was recorded using pairs of short sonic stimuli at 65 dB nHL (normal hearing level) with different intervals (0-32 ms). A computer was used to subtract a single short reaction from the paired shortness reaction to extract the derivatized ABR. The results showed that the amplitudes of ABR V waves derived from single and double ears were obviously affected when the paired short acoustic distance was 0.2 ~ 1.5ms. The amplitude of single-vessel and double-ear-derived ABR I wave was not significantly different between the two groups (P> 0.05) ). This result suggests that the high brainstem pathway not only reduces the ability of the ipsilateral ear to respond to the second short tone but also to the second short tone from the contralateral ear when the pairwise short sound interval is 0.2 to 1.5 ms. It is inferred that there may be bicep interactions in the inferior colliculus when the distance between the ears stimulated alternately by the two ears is less than 2ms. The results also suggest that the clinical examination of ABR, the use of short-sound stimulation interval should not be less than 30ms.