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Purpose: To observe the clinical effect of alomide and sodium cromoglycate eyedrops in the treatment of atopic conjunctivitis, val conjunctivitis and giant papillary conjunctivitis.Methods: Randomized control study was used. Alomide and sodium cromoglycate eyedrops used to treat two groups of patients for two weeks. The effects of the two groups were compared.Results: With respect of comprehensive therapeutic effect, the effectiveness rate was 83.6% in alomide group, and 63.3% in sodium cromoglycate group, which was not significantly different statistically. With respect of itching alleviation, alomide is more effective than sodium cromoglycate. No adverse effects were found in both groups.Conclusion: Our study suggests that alomide is a safe and effective drug in the treatment of allergic conjunctivitis.