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胎死宫内是产科常见问题之一,可以导致妊娠妇女心理压力、感染和凝血功能障碍等合并症。虽然有些几周内可以自然临产,但多数需要引产。最常使用的引产药物——缩宫素往往无效,尤其在妊娠不足月时。现已证实前列腺素(PGs)可用于死胎引产,PGE_2阴道后穹隆放置可有效地用于28周死胎引产。米索前列醇(简称米索)是作为PGE_1的衍生物,有报道其对死胎引产具有较好的疗效,且副作用小。
Intrauterine fetal death is one of the common obstetric problems that can cause psychological stress in pregnant women, infection and coagulopathy and other complications. Although it is natural for labor within a few weeks, most require induction of labor. Otorhinidazole, the most commonly used induction drug, is often ineffective, especially when the pregnancy is short. It has been confirmed prostaglandin (PGs) can be used for stillbirth induction, PGE_2 vaginal posterior fornix can be effectively used for 28 weeks of induced abortion. Misoprostol (referred to as misoprostol) is as a derivative of PGE_1, it has been reported that it has a good effect on induced abortion of the stillbirth, and the side effects are small.