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目的:临床实践研究奥美拉唑、阿莫西林联合呋喃唑酮口服(三联疗法)在抗幽门螺杆菌(HP)中的疗效及应用价值。方法:随机选择江苏省常州市新北区孟河人民医院2010年2月至2013年6月间诊治的100例幽门螺杆菌感染患者的临床治疗资料进行回顾性分析。结果:两组患者经临床治疗后,实验组患者的HP根治率为84%,而对照组仅为62%;在临床疗效方面,实验组的总有效率(96%)明显高于对照组(78%),组间不良反应无明显差异性。结论:通过长期临床研究证实,在HP感染患者中给予采取三联疗法可有效提升HP根除率,且安全可靠,比较适合在基层医院推广应用。
OBJECTIVE: To evaluate the clinical efficacy and safety of omeprazole and amoxicillin combined with furazolidone orally (triple therapy) in the treatment of Helicobacter pylori (HP). Methods: 100 cases of Helicobacter pylori infection were randomly selected from Menghe People’s Hospital of Xinbei District, Changzhou City, Jiangsu Province from February 2010 to June 2013 for retrospective analysis. Results: After the clinical treatment of two groups, the cure rate of HP in the experimental group was 84%, while the control group was only 62%. The total effective rate (96%) in the experimental group was significantly higher than that in the control group 78%), no significant difference between the adverse reactions. CONCLUSION: Long-term clinical studies have confirmed that the triple therapy in patients with HP infection can effectively improve the HP eradication rate and is safe and reliable, so it is more suitable for promotion and application in primary hospitals.